Description
SS-31, also known as Elamipretide, Bendavia, or MTP-131, is a synthetic peptide that targets and improves mitochondrial function. Mitochondria generate ATP (the body’s primary energy molecule), regulate cellular homeostasis, and impact nearly all physiological systems. SS-31 is a mitochondrial-targeted antioxidant with extensive therapeutic potential: mitigating oxidative stress, suppressing inflammation, maintaining mitochondrial health, and preventing cellular apoptosis.
It has several advantages over natural antioxidants and plays a key role in treating mitochondrial dysfunction-related disorders.
Benefits
- Increased energy (most potent energy-boosting peptide available)
- Neutralizes free radicals and reverses oxidative stress damage
- Anti-aging
- Anti-inflammatory (including neuroinflammation)
- Supports memory and cognition
- Antifibrotic
- Beneficial for kidney disease (activates AMPK pathway)
- Fights insulin resistance
- May prevent or mitigate symptoms of:
- Cardiovascular disease
- Neurodegenerative conditions
- Asthma and COPD
- Age-related macular degeneration
- Cancer
- Barth syndrome
- Primary mitochondrial myopathy
- Duchenne muscular dystrophy
- Friedrich’s ataxia
Possible Side Effects
- Injection site irritation (redness, swelling, and/or itching)
- Gas
- Gastrointestinal upset
- Headache
- Dizziness
- Signs of an allergic reaction include: fast, erratic heartbeat; profuse sweating; shortness of breath; confusion; severe weakness; loss of coordination; stiff muscles and high fever; eye symptoms including blurred vision, tunnel vision, eye pain, swelling of the eyes, seeing halos around lights
Contraindications
- Do not use if pregnant or breastfeeding
- Do not use if hypersensitive to mitochondrial-targeted compounds
RECONSTITUTION & DOSING
12-week cycle followed by 4-8 week washout period
Subcutaneous administration
MORNING DOSING
SS-31: 10mg STANDARD PROTOCOL
Mix with 1mL (100 units) of BAC water
10 units-20 units(1mg), 1x/day, 7 days/week
SS-31: 10mg MAXIMUM PROTOCOL
Mix with 1mL (100 units) of BAC water
Week 1: 10 units(1mg), 1x/day, 5 days/week
Weeks 2–5: 20 units (2mg), 1x/day, 5 days/week
Weeks 6–8: 30 units (3mg), 1x/day, 3 days/week
Weeks 9–12: 40 units (4mg), 1x/day, 3 days/week
SS-31: 30mg STANDARD PROTOCOL
Mix with 3mL (300 units) of BAC water
10-20 units (1-2mg), 1x/day, 7 days/week
SS-31: 30mg MAXIMUM PROTOCOL
Mix with 3mL (300 units) of BAC water
Week 1: 10 units(1mg), 1x/day, 5 days/week
Weeks 2–5: 20 units (2mg), 1x/day, 5 days/week
Weeks 6–8: 30 units (3mg), 1x/day, 3 days/week
Weeks 9–12: 40 units (4mg), 1x/day, 3 days/week
Stacking Suggestions
- MOTS-C – run before an SS-31 cycle for maximum mitochondrial optimization. SS-31 primes the mitochondria, MOTS-C boosts cellular adaptation and metabolic health (Follow standard protocol for 10-14 days prior to start of MOTS-C protocol)
- NAD+ – supports ATP production and cellular repair when paired with SS-31
- Glutathione – enhances antioxidant defense and detoxification during oxidative stress repair
- CJC-1295 / Ipamorelin – supports cellular regeneration and recovery alongside mitochondrial repair
- AOD-9604 – assists with fat metabolism during energy-focused SS-31 cycles
- BPC-157 – promotes systemic healing and combats inflammatory stress
All peptide instructions on this site are provided strictly for laboratory research and educational purposes. This information is not intended for human or veterinary use unless prescribed by a licensed medical professional.




